Acute Viral Hepatitis is the most common cause of jaundice in pregnancy. HBV infection during pregnancy is usually mild, not associated with increased mortality or teratogenicity, and should not prompt consideration of termination. Acute HBV infection may lead to perinatal transmission up to 60% if near time of delivery. If the mother remains HBsAg -positive or has detectable serum HBV DNA, the infant should receive HBV immune globulin in addition to the first dose of the hepatitis B vaccine at birth. Treatment is mainly supportive, but tenofovir disoproxil fumarate (300mg daily) – preferred – or lamivudine (100mg daily) are suitable if reduction of viral load is considered
Hepatitis B & Pregnancy